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Manish A. Shah, MD

Director, Gastrointestinal Oncology Program, Weill Cornell Medicine
Chief, Solid Tumor Oncology Service and Co-Director, Center For Advanced Digestive Care, New York Presbyterian Hospital

Manish A. Shah, the Bartlett Family Professor of Gastrointestinal Oncology, is recognized for his clinical and translational investigation focusing on drug development and advancing the care of gastrointestinal malignancies. He received a BES in Biomedical Engineering from Johns Hopkins University; MD from the Harvard/MIT Health Sciences and Training program; and completed his training in Oncology at Memorial Sloan Kettering / Weill Cornell Medicine, where he was chief fellow. Presently, his academic titles include Chief, Solid Tumor Oncology Service; Director, Gastrointestinal Oncology Program at Weill Cornell Medicine and Co-Director, Center for Advanced Digestive Care, New York Presbyterian Hospital. Dr. Shah was a former student at the Vail Workshop as a fellow at Memorial Sloan Kettering.

Dr. Shah’s current research interests include the following:

  1. Early Drug Development in Gastrointestinal Malignancies (phase I and II studies)
  2. Developing Targeted therapies in gastric and esophageal cancers, particularly with a focus on immunotherapy and immunotherapy combinations.
  3. Understanding the basis for resistance to taxanes in upper GI cancers.
  4. Understanding the gastric and esophageal microbiome and how that may affect regional immunity
  5. Defining disease subtypes of gastrointestinal malignancies to improve patient management and drug development.